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临床试验/NL-OMON33174
NL-OMON33174招募中不适用

Individual PEEP setting guided by End Expiratory Lung Volume with an Upper Pressure Limit in mechanically ventilated critically ill patients - EELVguidedPEEP

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 40 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
40

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • - >18 years of age
  • - Written informed consent from legal representatives
  • - Mechanical ventilation < 24 hour after intubation
  • - Requiring mechanical ventilation without acute respiratory failure (PaO2/FiO2 ratio > 300 mmHg)
  • - Requiring mechanical ventilation with acute respiratory failure (PaO2/FiO2 ratio > 300 mmHg)

排除标准

  • - Inability to perform reliable lung volume measurements
  • * Air leak
  • * Severe airflow obstruction due to COPD (forced Expired Volume in 1 sec or Vital Capacity below predicted value minus 2 SD
  • * Patients with known emphysema and the presence of bullae on X-ray
  • * Patients with pneumothorax on x-ray
  • - Inability to use the standard reference EELV values
  • * Thoracic deformities
  • - Severe hemodynamic instability

研究者

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