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Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea

Phase 1
Not yet recruiting
Conditions
Obstructive Sleep Apnea of Adult
Registration Number
NCT06295562
Lead Sponsor
China Medical University Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Not yet recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Inclusion Criteria:<br><br> - apnea-hypopnea index = 15 hr-¹<br><br>Exclusion Criteria:<br><br> - the presence of pulmonary, cardiac, neurologic, or other active severe medical or<br> psychiatric diseases<br><br> - current use of continuous positive airway pressure therapy<br><br> - use of drugs that might interact with the investigational medication or known to<br> affect sleep during the trial or 1 month before the study<br><br> - known allergy to the investigational medication<br><br> - current smoking<br><br> - heavy alcohol drinking (male > 14 drinks and women >7 drinks per week)<br><br> - pregnant or lactating<br><br> - periodic limb movement index = 15hr-1<br><br> - the presence of sleep-related hypoventilation

Exclusion Criteria

Not provided

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Physiological parameter
Secondary Outcome Measures
NameTimeMethod
Endotypic traits
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