Role of the Human Microbiome and covid-19 disease in hospital Acquired and Ventilator Associated pneumonia in critically ill patients
Recruiting
- Conditions
- U69.01
- Registration Number
- DRKS00024777
- Lead Sponsor
- niversitätsklinikum Leipzig Interdisziplinäre Internistische Intensivmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 1200
Inclusion Criteria
Age = 18 years
- signed consent
- icu treatment
- rise in SOFA Score = 2 points
- expected length of icu treatment > 72 h
Exclusion Criteria
- age < 18 years
- pregnant or breastfeeding women
- antibiotical therapy within last 30 days
- antibiotcal therapy for more than 24 h within index hospitalization
- transfer from icu within 72 h likely
- best supportive care / withhold or withdrawal of therapy
- death deemed likely or inevitable within next 72 h
- patients, that already participated in this study
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method genetic diversity / specific mutations in pathogen species
- Secondary Outcome Measures
Name Time Method days on ventilator, rate of organ dysfunction (acute kidney injury, shock) icu mortality