The Association of Gut Microbiota With COVID 19 Infection in Children

Recruiting

• Conditions: Gut Microbiome; Coronavirus Infections; Childhood ALL
• Interventions: Diagnostic Test: 16S rRNA sequencing

• Registration Number: NCT05303155
• Lead Sponsor: Hallym University Kangnam Sacred Heart Hospital

Brief Summary

Although COVID-19 infects gastrointestinal tissues, little is known about the roles of gut commensal microbes in susceptibility to and severity of infection. The investigators will analyze the alterations in fecal microbiomes of patients with COVID-19 infection during hospitalization.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-03-18
• Study First Submitted QC: 2022-03-28
• Study First Posted: 2022-03-31
• Study Start: 2022-04-14
• Status Verified: 2023-05
• Last Update Submitted: 2023-05-18
• Last Update Posted: 2023-05-19
• Primary Completion: 2023-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• patients infected with COVID 19

Exclusion Criteria

• congenital heart, renal, intestinal disease
• malignancy
• immunologic disease

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patient with COVID 19	16S rRNA sequencing	Pediatric patient infected by COVID 19
Pediatric patient without infection of COVID 19	16S rRNA sequencing	Pediatric patient without infection of COVID 19

Primary Outcome Measures

Name	Time	Method
The analysis of fecal microbiome of patient with COVID 19	through study completion, an average of 1 year	The analysis of fecal microbiome of patient with COVID 19, using 16S rRNA sequencing

Trial Locations

Locations (1)

Hallym University Kangnam Sacred Heart Hospital; 🇰🇷 Seoul, Korea, Republic of