ew method of levothyroxine dose estimation in primary Hypothyroidism
Not Applicable
- Conditions
- Health Condition 1: E038- Other specified hypothyroidism
- Registration Number
- CTRI/2021/07/034565
- Lead Sponsor
- Principal Investigator
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Age above 18 years and <60 years,
2.Newly diagnosed with primary hypothyroidism (overt and subclinical hypothyroidism)
3.Treatment-na�¯ve (not started on thyroid hormone treatment)
Exclusion Criteria
1.Pregnancy,
2.Central hypothyroidism,
3.Within two years of post-radiotherapy or radioiodine ablation,
4.Post total thyroidectomy cases,
5.Major co-morbidities,
6.Co-prescription of treatment known to affect thyroid hormone metabolism.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Euthyroidism at follow up <br/ ><br>We expect around 60 percent of the participants will achieve euthyroidism at first visit based on calculated doseTimepoint: follow up will be at 6-12 weeks after starting dose and each dose adjustment
- Secondary Outcome Measures
Name Time Method To estmate the incidence of Iatrogenic thyrotoxicosis in both armsTimepoint: At the 1st follow-up between 4-8 weeks of starting levothyroxine