Optimal prescribing of levothyroxine for underactive thyroid gland treatment

Not Applicable

• Conditions: Hypothyroidism; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN65030272
• Lead Sponsor: ewcastle upon Tyne Hospitals NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-10-18
• Last Update Posted: 20 November 2023
• Study Completion: 2025-01-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

1. Patients taking levothyroxine for more than 6 months
2. Aged 18 years and over
3. No documented serum TSH =10 mU/l recorded in electronic health records
4. Pregnancy, breastfeeding or with a plan for pregnancy within 6 months
5. No history of thyroidectomy, pituitary disease or thyroid cancer
6. No active ischaemic heart disease, arrhythmia or other condition that in the opinion of the principal investigator would render the withdrawal of thyroid hormone unsafe
7. No dementia, active psychotic or serious mental health condition
8. Ability to give written informed consent

Exclusion Criteria

Does not meet the inclusion criteria

Study & Design

• Study Type: Interventional
• Study Design: Not specified