itrous oxide and cerebral vasodilatation: a dose-response study in healthy volunteers
Phase 1
- Conditions
- The study will be conducted in healthy volunteers. I will evaluate the effects of inhaled concentrations of nitrous oxide, ranging from 0% to 50%, on cerebral blood flow and cerebral vascular tone in a dose related manner.
- Registration Number
- EUCTR2007-007094-23-GB
- Lead Sponsor
- niversity of Nottingham
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
•Healthy volunteers aged between 18 and 50 years
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
•History or evidence of a systemic illness or vascular disease
•On prescription medication which may affect cardiovascular system
•Any evidence of neurological disorder
•Previous neurological surgery
•Smokers
•Pregnant or lactating females
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method