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Comparative study of therapeutic effects of Gabapentin versus Levodopa-c on Restless legs syndrome in hemodialysis patientes

Not Applicable
Conditions
RLS: Restless Legs syndrome..
Other specified extrapyramidal and movement disorders
G 25.8
Registration Number
IRCT201112078323N1
Lead Sponsor
Sponsor name 1 Vice-chancellor of Research and Technology of Kermanshah University of Medical
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Inclusion criteria :minimal time of hemodialysis : 3 mount ?IRLSSG scale more than 10? Patient`s age more than 15 years
Exclusion criteria: Under treatment with psychotropic agents during recent 2 weeks?presence of another neurologic disease comorbid with ESRD for example CVA, MS and etc.?Iron deficiency anemia?Pregnancy

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Severity of RLS. Timepoint: At first &4 wks after first drug administration before second drug administration & 4 wks after second drug administration (end of the study). Method of measurement: with IRLSSG scale.;Severity of sleep disorder. Timepoint: At first &4 wks after first drug administration before second drug administration & 4 wks after second drug administration (end of the study). Method of measurement: with pittsburg sleep quality index.;Quality of life. Timepoint: At first &4 wks after first drug administration before second drug administration & 4 wks after second drug administration (end of the study). Method of measurement: with SF-36 (scale of quality of life).;Day time sleepiness. Timepoint: At first &4 wks after first drug administration before second drug administration & 4 wks after second drug administration (end of the study). Method of measurement: Epworth sleepiness scale.
Secondary Outcome Measures
NameTimeMethod
Drug advers reaction. Timepoint: At first &4 wks after first drug administration before second drug administration & 4 wks after second drug administration (end of the study). Method of measurement: with question from patients.
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