Combination therapy using calcium/vitamin D and protein/calorie supplements in nutritionally deficient wome

Completed

• Conditions: Osteoporosis; Musculoskeletal Diseases

• Registration Number: ISRCTN62937696
• Lead Sponsor: Action Medical Research (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2001-03-01
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 71

Inclusion Criteria

1. Women over 70 years
2. Body mass index of less than 21 kg/m^2
3. Osteoporosis at the femoral neck and/or total hip

Exclusion Criteria

1. Evidence of any progressive wasting disease, e.g. carcinomatosis, severe malabsorption
2. Severe renal impairment (estimated glomerular filtration rate [GFR] less than or equal to 45 ml/min)
3. Severe cardiorespiratory diseases
4. Endocrine diseases, e.g., hyperparathyroidism, hyperthyroidism
5. Therapy with drugs known to interfere with bone metabolism such as steroids, vitamin D or its derivatives, bisphosphonates, oestrogen, raloxifene
6. Cognitive impairment (abbreviated mental test score 7 or below)

Study & Design

• Study Type: Interventional
• Study Design: Not specified