A randomized placebo controlled trial of a combination of acyclovir, benzathine penicillin and ciprofloxacin versus a combination of placebo, benzathine penicillin and ciprofloxacin for the syndromic treatment of genital ulcer disease in Malawi
Completed
- Conditions
- Genital Ulcer Disease (GUD)Urological and Genital Diseases
- Registration Number
- ISRCTN32121857
- Lead Sponsor
- niversity of North Carolina (USA)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
1.Age 18 years or older
2.Clinically confirmed genital ulcer(s)
3.Ability to provide informed consent for participation, examination and sample collection
4.Willingness to be counselled
5.Tested and received results for HIV and other STIs
6.Resident in Lilongwe catchment?s area and with intention to stay for at least one month
Exclusion Criteria
1.Younger than 18 years old
2.Known allergy to penicillin, erythromycin, acyclovir, or ciprofloxacin
3.Patients with known or evidence of renal impairment
4.Very sick requiring admission
5.Women currently menstruating
6.Pregnant or lactating mothers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method