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Coagulation abnormalities following brain hemorrhage

Not Applicable
Recruiting
Conditions
Health Condition 1: null- Subarachnoid hemorrhage
Registration Number
CTRI/2011/10/002085
Lead Sponsor
Indian Council of Medical Research
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

We will enroll 20 adult patients scheduled to undergo intracranial aneurysmal clipping.

Exclusion Criteria

Patients with history of coagulopathies, those on anticoagulant and non-steroidal anti-inflammatory analgesic drugs, pediatric patients, history of intracranial surgery, trauma and non-consenting patients would be excluded from the study.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To assess the coagulation profile of patients with aneurysmal subarachnoid hemorrhage in different Hunt and Hess grades, during the perioperative period, as evaluated using the TEG.Timepoint: 1.A baseline sample, taken immediately after induction of general anesthesia. [Sample 1] <br/ ><br>2.Five minutes post-clipping of aneurysm. [Sample 2] <br/ ><br>3.Postoperative, after last skin suture. [Sample 3] <br/ ><br>4.24 hours postoperative, in the ICU. [Sample 4] <br/ ><br>
Secondary Outcome Measures
NameTimeMethod
To assess the effect of coagulation profile on the postoperative course of these patients in the intensive care unit (ICU).Timepoint: 1.Duration of ICU and Hospital stay <br/ ><br>2.Condition at discharge.
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