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临床试验/NCT02812797
NCT02812797已完成不适用

Prognostic Value of Adipokine Levels of Patients With Chronic Heart Failure

Chongqing Medical University1 个研究点 分布在 1 个国家目标入组 98 人开始时间: 2016年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
98
试验地点
1
主要终点
All-cause mortality

研究概览

简要总结

The purpose of this study is to determine whether expressions of adipokines can provide prognostic information concerning patients with chronic heart failure.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
12 Years 至 80 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who are giving open chest surgical treatment with a history of chronic heart failure (NYHA II ~ IV) more than 6 months.
  • Patients from whom informed consent has been properly obtained in writing prior to start of the trial.

排除标准

  • Patients with concurrent infection or any documented inflammatory illness, such as arthritis or connective tissue diseases,or any other malignancy.
  • Patients with a history of cardiomyopathy.
  • Patients with Chronic arrhythmia.
  • Pregnant women
  • Severe hepatic dysfunction or End-stage renal failure.
  • Uncontrolled hypertension.

结局指标

主要结局

All-cause mortality

时间窗: Change from Baseline at 3, 6 and 12 months

次要结局

  • Cardiac transplantation(Change from Baseline at 3, 6 and 12 months)
  • Cardiovascular death(Change from Baseline at 3, 6 and 12 months)
  • plasma brain natriuretic peptide (BNP) concentration(Week:4)
  • New York Heart Association (NYHA) Classification(Week:4)
  • re-hospitalization(Change from Baseline at 3, 6 and 12 months)

研究者

发起方
Chongqing Medical University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Dongying Zhang

Dr

Chongqing Medical University

研究点 (1)

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