The effects on two conventional medication, acetaminophen and loxoprofen, for musculoskeletal pain including neck pain, low back pain, and knee pain. -multicenter longitudinal study
Not Applicable
- Conditions
- Musculoskeletal pain
- Registration Number
- JPRN-UMIN000025797
- Lead Sponsor
- Japanese assocation for the study of muskuloskeletal pain, division of clinical reaseach
- Brief Summary
The results suggest that acetaminophen has comparable analgesic effects on acute LBP, based on at least a noninferiority margin, compared with loxoprofen at 4 weeks. Acetaminophen seems to be a reasonable first-line option for patients with acute LBP in Japan.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 310
Inclusion Criteria
Not provided
Exclusion Criteria
1)The subjects just seek second opinion. 2)History of malignant disease. 3)The subjects with surgical histories within six month. 4)The subjects considered inappropriate by the attending doctor.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bio-equivalence of the effects on two conventional medications for pain reduction in musculoskeletal pain.
- Secondary Outcome Measures
Name Time Method Pain Disability Assessment Scale, Hospital Anxiety and Depression Scale, Pain Catastrophizing Scale, Work Productivity and Activity Impairment, Euro-QOL 5 Dimension, Adverse effect, Laboratory examination.