Evaluation of the healthy liver using new magnetic resonance imaging and spectroscopy methods at 3.0T and 7.0T
- Conditions
- Non-alcoholic fatty liver disease10019654
- Registration Number
- NL-OMON36052
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 30
Healthy volunteers, 18 years or older
Written informed consent
- Healthy volunteers under 18 years of age
- Alcohol consumption of >3 units/day for males and >2 units/day for females (steatogenic effect)
- Contraindications for MRI (with the use of standard MRI checklist, see document E4)
- Body Mass Index (BMI) >27 (there is a high prevalence of hepatic steatosis in overweight persons)
- Diabetes Mellitus
- History of or current treatment for liver disease
- Use of medications known to have steatogenic effects on the liver: synthetic estrogens, corticosteroids, diltiazem, nifedipine, perhexilline, amiodarone, metformine, insulin, statins, rosiglitazon, methotrexate, antiretroviral therapy, tamoxifen, tetracycline, valproate
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method