Comparison of Transdermal Buprenorphine and Diclofenac patch for post operative pain relief in patients undergoing major lower limb orthopaedic surgeries

Not yet recruiting

Conditions: Medical and Surgical,

Registration Number: CTRI/2021/08/035857

Lead Sponsor: GOVERNMENT MEDICAL COLLEGE BHAVNAGAR

Brief Summary: After taking approval from ethics committee, study will be initiated on patients fulfilling inclusion criteria, patients will be assessed for post operative pain according to VAS scale, need for rescue analgesia with in 24 hours of post operative period and side effects like nausea, vomiting and pruritis.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 50

Inclusion Criteria

1.Elective and emergency orthopaedic surgery patients with lower limb long bone fractures 2.Age group:18-60 years 3.ASA grade I- III.

Exclusion Criteria

1.Patients having injuries over other parts of body rather than lower limb 2.Altered coagulation profile and spinal deformities(Kyphosis, Scoliosis) 3.Suffering from respiratory disease, severe hepatic and renal dysfunction 4.Pregnant and lactating mother 5.Hypersensitivity to study drugs.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.To compare the post-operative analgesia by visual analogue scale between both groups	24 HOURS
2.To compare frequency of need for rescue analgesia between both groups	24 HOURS

Secondary Outcome Measures

Name	Time	Method
1.To compare change in pulse rate, mean arterial pressure, Spo2, respiratory rate between both groups.	2.To compare the proportion of post-operative nausea, vomiting, PruritiS between both groups

Trial Locations

Locations (1): SIR T GENERAL HOSPITAL, BHAVNAGAR
🇮🇳
Bhavnagar, GUJARAT, India
SIR T GENERAL HOSPITAL, BHAVNAGAR
🇮🇳Bhavnagar, GUJARAT, India
PAMPANA BHUVAN CHANDRA KANTH
Principal investigator
8978908092
bhuvanthedoc2805@gmail.com