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A clinical trial to study the changes in biomarkers of saliva and blood in males with alcohol dependence syndrome, before and after deaddiction treatment.

Not Applicable
Conditions
Health Condition 1: null- Alcohol Dependence syndrome
Registration Number
CTRI/2015/01/005372
Lead Sponsor
Father muller medical college
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
114
Inclusion Criteria

1)Males in the age group of 18-65 years

2)Group I : diagnosed of alcohol dependence by the treating psychiatrist, based on The ICD-10 (the 10th revision of the International Statistical Classification of Diseases ) Classification of Mental and Behavioural Disorders : Diagnostic Criteria for research of WHO .1,2 currently using substance and smokers

3) Group II : diagnosed of alcohol dependence by the treating psychiatrist, based on The ICD-10, DCR of WHO .1,2 currently using substance and non-smokers.

4) Group I(a) & Group II (a) : diagnosed of alcohol dependence by the treating psychiatrist, based on The ICD-10, DCR of WHO .1,2 currently abstinence, smokers and non-smokers, respectively.

5) Group III : Age matched, apparently healthy non-alcoholic, non smoker male volunteers

Exclusion Criteria

1)Age : < 18 years and > 65 years.(all groups)

2)Use of substances (control group)

3)Systemic illness: Non alcoholic liver disease, kidney disease, cancer, inflammatory diseases, infections, etc.(all groups)

4)Lost for follow up or those who withdrew from study(all groups)

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Salivary biochemical parameters as biomarkers of alcohol dependence.Timepoint: Salivary biochemical parameters as biomarkers of alcohol dependence.
Secondary Outcome Measures
NameTimeMethod
Alcohol deaddiction will ameliorate the salivary biochemical parametersTimepoint: 30 days
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