Comparing oral and intravenous paracetamol plasma levels when given as pre-medication for peri-operative analgesia

orth Bristol NHS Trust (UK)0 个研究点目标入组 104 人开始时间: 2006年11月28日最近更新: 2015年1月13日

试验速览

暂无简介。

•1. Assessment of fitness as indicated by the American Society of Anesthesiologists (ASA) grades I and II
•2. Age group 16 to 75 years
•3. All patients listed for elective surgery by Mr P Robinson on a Thursday for Ear, Nose & Throat surgery

•1. Patients refusing to participate in study
•2. Patient unable to take an oral preparation
•3. Cases shorter than one hour
•4. Patients already taking a paracetamol containing drug combination, or have taken in the last 12 hours
•5. Patients with a history of paracetamol allergy, hypersensitivity or previous reaction/serious adverse reaction
•6. Children under the age of 16
•7. Patients unable to understand or give consent to participation in the study; incapable adults, psychiatric/medical disorder able to modify patient compliance
•8. Pregnant or breastfeeding
•9. History of complete non-responsiveness to acetaminophen
•10. Pancreatic disease in the previous 12 months
•11. Impaired liver/kidney function
•12. Patients that might pose an infection risk to staff due to blood products

发起方

orth Bristol NHS Trust (UK)