Trancriptome patterns in dermal schwann cells in neuropathic itch and pai
Recruiting
- Conditions
- Pruritus, unspecifiedG62Other polyneuropathiesL29.9
- Registration Number
- DRKS00026173
- Lead Sponsor
- niversitätsklinikum Würzburg Neurologische Klinik
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 570
Inclusion Criteria
For screening:
Diagnosis of peripheral neuropathy
For participation in the other parts of the study:
Diagnosis of peripheral neuropathy OR diagnosis of brachioradial pruritus OR healthy control subject.
Additional inclusion criterion for peripheral neuropathy:
In the diary over one week, moderate pain = NRS 5 and, pruritus = 1 OR moderate pruritus = 5, pain = 1.
Exclusion Criteria
Other serious illness that would falsify the examination results or make participation difficult, known wound healing disorders or anticoagulation (due to skin biopsy).
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Expression of IF144L in the skin
- Secondary Outcome Measures
Name Time Method Itch severity under C-fibre stimulation