Noninvasive Estimation of Work of Breathing
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Acute Respiratory Distress Syndrome
- Sponsor
- Respironics, California, Inc.
- Enrollment
- 5
- Locations
- 1
- Primary Endpoint
- Accuracy of lung mechanics measurements
- Status
- Terminated
- Last Updated
- 8 years ago
Overview
Brief Summary
This study will evaluate the correlation between invasively measured parameters (work of breathing/power of breathing, resistance and elastance), derived using esophageal pressure measurements, and their corresponding non-invasive estimated values (noninvasive work of breathing/power of breathing, resistance and elastance), computed using airway pressure and flow measurements only.
Detailed Description
This study will evaluate the correlation between invasively measured parameters (work of breathing/power of breathing, resistance and elastance), derived using esophageal pressure measurements, and their corresponding non-invasive estimated values (noninvasive work of breathing/power of breathing, resistance and elastance), computed using airway pressure and flow measurements only. Vent settings will be adjusted to test accuracy over a range of respiratory support conditions.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adult medical/surgical ICU patients (Age≥18) on mechanical ventilation for respiratory failure, spontaneously breathing and receiving eligible for pressure support ventilation (PSV).
Exclusion Criteria
- •Prisoners and patients with closed-head injury (e.g., trauma), hemodynamic instability, multiple organ system failure or late term pregnancy will not be studied.
Outcomes
Primary Outcomes
Accuracy of lung mechanics measurements
Time Frame: Immediate