A Comparison Study About Does Reduced Sitting Time Improves the Memory Functions and Brain Blood Supply?
Phase 2
- Registration Number
- CTRI/2021/09/036496
- Lead Sponsor
- Obhuli Chandran M
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Participants working in offices (desk-based jobs), Who are willing to practice with the age of 25 â?? 38 years, with low physical activity based on International Physical Activity The questionnaire will be considered for the study and who are willing to participate in the study by signing informed consent.
Exclusion Criteria
History of cardiovascular or metabolic disorders, Family history of carotid artery disease and cardiovascular disorders, Persons with psychiatric disorders who are under medication, Bone diseases like Osteomalacia and bone tumor, neuromuscular diseases hindering from adequate activity participation during the study period, drugs altering the vascular function.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Doppler ultrasound scan will be performed to determine the Velocity and artery diameter of the Carotid artery and Superficial Femoral Artery. Further, Carotid artery and Superficial Femoral artery endothelial Shear Stress will be measured. A 7 to 15 Â MHz multi-frequency linear array probe attached to a highâ??resolution Doppler machine will be used to note the readings obtained. <br/ ><br>Timepoint: During the first day of the study i.e., the first week of the trial.
- Secondary Outcome Measures
Name Time Method By the help of Inquisit licensed software the collected data of Cognitive functions will be measured with Eriksen Flanker tests (Inhibition, reaction time and accuracy for the Flanked and Non flanked stimuli ) <br/ ><br>N Back memory tests(Working memory, reaction times and accuracy for the stimuli ). <br/ ><br>Timepoint: The final outcomes will be assessed during the 3rd day of the study. i.e., the third week of the trial of the participants.