Prevention of Delirium (POD) for older people in hospital - a feasibility study

Not Applicable

Completed

• Conditions: Topic: Generic Health Relevance and Cross Cutting Themes; Subtopic: Generic Health Relevance (all Subtopics); Disease: Age and ageing; Mental and Behavioural Disorders; Delirium, unspecified

• Registration Number: ISRCTN01187372
• Lead Sponsor: Bradford Institute for Health Research (UK)

Brief Summary

2015 Protocol article in http://www.ncbi.nlm.nih.gov/pubmed/26253332 protocol 2019 Results article in https://www.ncbi.nlm.nih.gov/pubmed/30991945 results 2020 Results article in https://www.ncbi.nlm.nih.gov/pubmed/32307515 results (added 21/04/2020) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33819001/ (added 28/10/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-03-13
• Study Completion: 2015-07-03
• Last Update Posted: 7 November 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 714

Inclusion Criteria

All patients aged 65 years or older who do not have delirium when admitted to any elderly care/geriatric medicine or orthopaedic trauma/orthopaedic surgery wards taking part in the study will be assessed and given the opportunity to join.

Exclusion Criteria

1. Patients with prevalent delirium diagnosed by completion of the Confusion Assessment Method
2. Patients with a planned discharged from hospital within 48 hours of admission (established from information provided by the ward staff)
3. Patients where a delirium assessment (i.e. CAM) has not been performed within 24 hours of admission to the ward (for elderly care patients) or pre-operatively (e.g. fracture patients)
4. Patients who have not provided consent or consultee declaration for trial participation within 48 hours of admission to the ward
5. Patients receiving end of life care (because it is unlikely follow-up data will be available for these patients)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Estimate effectiveness through calculating incidence of delirium within 10 days of hospital admission<br> 2. Estimate cost-effectiveness<br> 3. Assess intervention delivery<br> 4. Estimate recruitment uptake and follow-up rates<br> 5. Assess completeness of follow-up data collection<br> 6. Assess degree of contamination<br> 7. Estimate cost-effectiveness<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Number, severity and length of delirium episodes (including persistent delirium at 30 days post admission)<br> 2. Length of stay<br> 3. Death<br> 4. Discharge destination<br> 5. Health outcome as measured by the EQ5D at baseline, 30 days and 3 months<br> 6. Physical and social independence as measured by the NEADL at baseline and 3 months<br> 7. Depression as measured by the Geriatric Depression Scale at 30 days<br> 8. Anxiety as measured by the Clincial Anxiety Scale at 30 days<br> 9. Patient experience as measured by the Patient Reported Experience Measure from the National Audit of Intermediate Care at 30 days<br> 10. Health and social care economic resource as measured by the trial-specific Health Economic resource use questionnaire at 30 days<br>