Investigating the Effects of Cardiac Rehabilitation eXercise Modalities on Physical and Mental Health Outcomes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 135
- 试验地点
- 2
- 主要终点
- Exercise Capacity
研究概览
简要总结
Coronary revascularization improves survival for patients with coronary artery disease. However,many patients are left with poor physical and mental health. Traditional cardiac rehabilitation involves moderate intensity continuous exercise (MICE). Alternatives to traditional cardiac rehabilitation programming may however provide superior understudied benefits to patients with poor physical and mental health. Nordic walking (NW) and high-intensity interval training (HIIT) are two examples of alternative programs for cardiac rehabilitation, which may provide superior physical and mental health benefits when compared to traditional MICE. The main purpose of this project is, therefore, to determine the short and long term physical and mental health benefits of alternative cardiac rehabilitation modalities, including NW and HIIT on exercise capacity, quality of life and depression after a 12-week program.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient with CAD who recently underwent PCI (within 2-10 weeks) PCI or coronary artery bypass grafting (within the last 18 weeks);
- •Patient is referred to University of Ottawa Heart Institute cardiac rehabilitation program;
- •Patient is able to walk independently
- •Patient is willing to attend an onsite cardiac rehabilitation program twice weekly for 12 weeks;
- •At least 40 years of age;
- •Patient is willing and able to provide informed consent
排除标准
- •Currently participating in routine exercise training (>2x/week) and/or using Nordic Walking poles;
- •Active infection or inflammatory condition;
- •Over 75 years of age;
- •Persistent or permanent atrial fibrillation;
- •Pregnant, lactating or planning to become pregnant during the trial period;
- •Unstable angina or established diagnosis of chronic obstructive pulmonary disease, severe mitral or aortic stenosis, or hypertrophic obstructive cardiomyopathy;
- •Unable to read and understand English or French;
- •Unwilling or unable to return for follow-up visit at weeks 12 and 26;
结局指标
主要结局
Exercise Capacity
时间窗: Baseline to 12 weeks and Baseline to 26 weeks
Changes in exercise capacity from baseline to 12 weeks and baseline to 26 weeks are measured by the six-minute walk test
次要结局
- Functional Fitness(Baseline to 12 weeks and Baseline to 26 weeks)
- Aortic stiffness(Baseline to 12 weeks and Baseline to 26 weeks)
- Depression(Baseline to 12 weeks and Baseline to 26 weeks)
- Quality of Life - HeartQoL(Baseline to 12 weeks and Baseline to 26 weeks)
- Exercise Adherence(Baseline to 12 weeks and Baseline to 26 weeks)
- Quality of Life - SF36(Baseline to 12 weeks and Baseline to 26 weeks)
- Lipid and glucose profile(Baseline to 12 weeks and Baseline to 26 weeks)
- Body Composition(Baseline to 12 weeks and Baseline to 26 weeks)
- Depression mechanisms(Baseline to 12 weeks and Baseline to 26 weeks)