Effect of sedation with dexmedetomidine on local anaesthesia.
Not Applicable
- Conditions
- Health Condition 1: null- Trauma or other surgery of upper limb
- Registration Number
- CTRI/2014/08/004818
- Lead Sponsor
- Indira Gandhi Institute of medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1. ASA grade 1 & 2
2, Patient scheduled for upper extremity surgery where supraclavicular brachial plexus block is indicated
Exclusion Criteria
1. known contraindication to brachial plexus block (patient refusal, coagulopathy, local infection)
2. known allergy to bupivacaine, midazolam and dexmedetomidine
3. concommittant us of analgesics or sedatives
4. history of significant cardiovascular, respiratory, neurological, psychiatric, hepatic or renal disease
5. failed brachial plexus block
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. onset and duration of motor block in minutes <br/ ><br>2. onset and duration of sensory block in minutesTimepoint: 0,5,10,15,30,45,60,90,120,150, 180,210,240,270,300,330,360,390,420,450,480,510,540,570,600 minutes
- Secondary Outcome Measures
Name Time Method 1. incidence of hypotension (Mean arterial pressure less than 20% of baseline value) <br/ ><br>2. incidence of bradycardia (Heart rate less than 50 BPM)Timepoint: 0, 10,20,30,40,50,60,70,80,90,120,150 minutes 180,210,240,270,300,330,360,390,420,450,480,510,540,570,600 minutes