跳至主要内容
临床试验/NCT02326701
NCT02326701Unknown不适用

RV Function by Strain and MRI

Hadassah Medical Organization1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2014年12月最近更新:
适应症

试验速览

阶段
不适用
入组人数
200
试验地点
1
主要终点
Correlation of 2D Echo and Echo strain measurements versus MRI measurements

研究概览

简要总结

Echocardiographic assessment of right ventricular function is an important diagnostic tool, and is a challenge due to the unique structure and anatomy of the right ventricle. Lately a new technique has been developed and used for evaluating both the left and the right ventricle function. This technique, called two dimensional (2D) speckle tracking, is based on detecting speckles in the myocardial tissue and using them as acoustic markers. The movement of these speckles represents the movement of the tissue, and allows us to evaluate its function, contraction and relaxation, this by calculating the strain rate, which is the speed of the speckles, and the strain, which is the distance between them.

In the last few years this technique has been used to evaluate the systolic function of the right ventricle in several pathological conditions, such as pulmonary hypertension, pulmonary embolism and amyloidosis. Nonetheless, so far there has been little data on the normal RV strain and strain rate values.

In this study the investigators aim to validate two dimensional (2D) speckle tracking measurements of the RV function by comparing them to strain measurements by cardiac MRI. Each patient performing cardiac MRI for any indication will perform an echocardiography examination in addition, and strain analysis performed on the cardiac MRI will be compared with two dimensional speckle tracking analysis performed on the echocardiography.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age: More than 18

排除标准

  • Age: Children
  • Unconcious patients.

结局指标

主要结局

Correlation of 2D Echo and Echo strain measurements versus MRI measurements

时间窗: 1 year

RV dimensions, RV function, RV strain measurements compared to MRI measurements

次要结局

  • Rehospitalization(2 years)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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