Effect of Aerobic Training on Quality of Life in Elderly With Idiopathic Chronic Fatigue

Not Applicable

Not yet recruiting

• Conditions: Chronic Idiopathic Fatigue
• Interventions: Other: Aerobic training

• Registration Number: NCT06203535
• Lead Sponsor: Pharos University in Alexandria

Brief Summary

the study was conducted to evaluate the effectiveness of aerobic training for decreasing fatigue severity and increasing quality of life in elderly with idiopathic chronic

Detailed Description

idiopathic chronic fatigue (ICF) or chronic idiopathic fatigue (CIF), this type of tiredness is ongoing and unrelated to any underlying medical or mental health issues. Different diagnostic criteria apply to people with idiopathic chronic fatigue and those with chronic fatigue syndrome (CFS).

Regular aerobic exercise has been demonstrated to improve cardiopulmonary fitness, increase physical activity levels, and decrease the degree of fatigue in elderly patients with severe idiopathic fatigue.

Study Timeline

• Status Verified: 2023-12
• Study First Submitted: 2023-12-11
• Study First Submitted QC: 2023-12-26
• Study First Posted: 2024-01-12
• Last Update Submitted: 2024-02-09
• Study Start: 2024-02-10
• Last Update Posted: 2024-02-13
• Primary Completion: 2024-04-13
• Study Completion: 2024-05-07

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Not provided

Exclusion Criteria

• Renal, vascular, hepatic, autoimmune, heart, chest and thyroid disorders.
• Lower limb arthritis or any orthopedic problem will hinder the training.
• Cognitive impairment or psychological problems,
• fatigue caused as a known side effect of medication.
• any febrile condition and/or infectious diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Aerobic training (group a)	Aerobic training	In addition to the standard physical therapy exercise programme (which includes flexibility and balance exercises), twenty individuals with idiopathic chronic fatigue will participate in an aerobic training group and walk for 45 minutes on a treadmill three times a week for two months. The workouts began with a five- to ten-minute warm-up on the treadmill and concluded with an equally extended cool-down. Using the Karvonen method, for exercise intensities ranging from 60 to 75 per cent of heart rate reserve during a 35-minute group cumulative exercise session.
control group (group B)	Aerobic training	twenty participants have idiopathic chronic fatigue will received only traditional physical therapy exercise program (flexibility and balance activities)

Primary Outcome Measures

Name	Time	Method
fatigue severity assessment scale	2 month will take pre and post total study peroid	Before and during the study period, the physical and mental weariness of both groups (A and B) was measured using a straightforward ten-item fatigue scale. The participants rated an etch statement from five categories, from never to always, using a scale. 1 denotes never, 2 occasionally, 3 regularly, 4 often and 5 always worn out. The greater figure denotes an extremely high degree of exhaustion and fatigue.
six mints walk test	2 monthes will take pre and post total study peroid	Before and during the study period, the aerobic capacity and endurance of both groups (A and B) were assessed using this sub-maximal test. The outcomes were compared to see how the performance capacity changed with walks lasting longer than six minutes.
Older People's Quality of Life Questionnaire (OPQOL-brief):	2 monthes will take pre and post total study peroid	Thirteen items make up the questionnaire; one item includes codes of Strongly agree (1), Agree (2), Neither (3), Disagree (4), and Strongly disagree (5). Positive items are reverse coded to indicate higher quality of life (QoL) with higher scores once all of the questions have been added up to give an overall OPQOL-Brief score.
Glutathione blood test:	2 monthes will take pre and post total study peroid	Glutathione is an antioxidant, a type of chemical which helps to boost the immune system as well as prevent and reverse cellular damage. Glutathione levels tend to decrease naturally with age as well as due to health conditions such as liver disease, insomnia, and chronic disease.Before and after the study period, venous blood was taken from both groups (A and B) at baseline when they were not fasting. Tandem mass spectroscopy was used to analyse the samples and determine the degree of serum changes in both study groups based on their respective treatment.