ISRCTN82559457已完成未知
Comparison of an automated weaning programme and a standard clinical weaning protocol for weaning critically ill patients: a randomised controlled trial
Guy's and St. Thomas' NHS Foundation Trust (UK)0 个研究点目标入组 500 人开始时间: 2005年9月30日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 500
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Added as of 10/12/2007:
- •Major entry criteria (suspected or proven infection, presence of a systemic response to the infection within the 48-hour period immediately preceding enrolment into the study, have or have had one or more sepsis-induced organ failures within the 48-hour period immediately preceding enrolment into the study).
- •1. Age >=18 years
- •2. Acute Physiology and Chronic Health Evaluation II (APACHE II) score =10
- •3. Precipitating injury (surgery, trauma, hypovolemia, episode of infection or sepsis) occurred within the last 48 hours before Intensive Care Unit (ICU) entry
- •4. Expected Length Of Stay (LOS) in the ICU >3 days
- •5. Indication for enteral nutrition for 5-10 days
- •6. Start of nutritional therapy with Intestamin or control supplement within 24 hours after inclusion criteria are fulfilled
排除标准
- •1. Under 18 years of age
- •2. Requirement for high doses of vasopressor
- •3. Body temperature greater than 39ºC or less than 36ºC
- •4. GCS = 12 without or with minimal sedation
- •5. 'Do Not Resuscitate' order or expected short term prognosis
- •6. Patients chronically ventilated at home with tracheostomy
- •7. Patients with primary neurological cause of ventilator dependence
- •8. Pregnancy
- •9. Prolonged cardiac arrest with poor neurological prognoses
- •10. Inability to obtain consent from patient or legal representative
研究者
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