EEG-correlated functional MRI in the planning of presurgical intracranial EEG recordings in intractable focal epilepsy

Completed

• Conditions: focal epilepsy; 10039911

• Registration Number: NL-OMON31477
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

all patients who are to undergo intracranial EEG evaluation (electrode implantation) in the UMCU, as part of the diagnostic protocol as decided by the National Dutch Taskforce on Epilepsy Surgery

Exclusion Criteria

A lack of interictal spiking in the standard EEG, defined as less than 10 spikes per hour. Contraindications for MRI, such as claustrofobia or presence of a pacemaker etc.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Cortical area (gyral location, surface delineation) of the epileptic source.<br /><br>Difference (location, surface) between predicted source with EEG-fMRI and gold<br /><br>standard (intracranial EEG).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Successful seizure outcome after 1 year postresection.</p><br>