Comparison of Deferazirox and Deferoxamine on Serum Ferritin Levels Changes in Major Beta Thalassemia Patients

Not Applicable

• Conditions: beta thalassemia major.; Beta thalassemia; D56.1

• Registration Number: IRCT20190817044550N4
• Lead Sponsor: Birjand University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 June 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

The age of the patients was 2 years and older
Have a normal serum creatinine level
Absence of proteinuria in U/A patients
The serum ferritin levels of the patients should be above 1000 mg/dl, or the patients should have had more than 10 blood transfusions, or the volume of blood transferred should be more than 100 cc/kg

Exclusion Criteria

Pregnancy and breastfeeding
Resistant levels greater than 5 times the normal value of liver transaminase
Severe nausea and vomiting in the patient
Patient refusal to participate in the study

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum ferritin level. Timepoint: Measurement of serum ferritin level at the beginning of the study (before the start of the intervention), 3 and 6 months after the start of the intervention. Method of measurement: Biochemical test.