Brush cytology; mesh brush versus conventional brush in Barrett*s esophagus

Completed

• Conditions: 1) Barrett esophagus 2) changed cell lining in the oesophagus; more likely to develop into cancer; 10017990; 10017991

• Registration Number: NL-OMON35631
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

Patients with Barrett esophagus who will undergo already planned upper endoscopy for routinely surveillance purposes.

Exclusion Criteria

Age under 18 year
Patients with ASA-score * 3

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>* the feasibility of brushing with a new developed mesh brush (compared to<br /><br>conventional brush)<br /><br>* the amount of cells obtained with the new mesh brush and with conventional<br /><br>brush</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>* the efficiency of the new brush device (time required to obtain brush<br /><br>specimen).<br /><br>* the quality of the obtained material for analysis with FISH-technique<br /><br>(fluorescence in situ hybridisation).<br /><br>* the material that remains for other techniques for DNA-, RNA- and<br /><br>protein-analysis.<br /><br>* any bleedings or discomfort leading to prolonged hospital<br /><br>stay.</p><br>