Perioperative Factors and Living Donor Liver Transplantation
- Conditions
- Liver Transplant Disorder
- Interventions
- Other: remote ischemic preconditioning (RIPC)
- Registration Number
- NCT06312098
- Lead Sponsor
- Min Suk Chae
- Brief Summary
Liver transplant surgery is one of the treatments provided to patients suffering from end-stage liver disease, and has a successful treatment prognosis. However, it is clear that patient management before, during, and after surgery is a difficult task for medical staff due to the complex clinical and pathological problems of end-stage liver disease. Moreover, the complex surgical technique of the liver transplant surgery itself and the severe hemodynamic fluctuations and multi-organ dysfunction that patients experience during the surgery have been shown to have a tremendous impact on the patient's prognosis after surgery.
A study on which clinical, laboratory, and hemodynamic factors experienced by patients during the perioperative period, including before, during, and after surgery, affect the survival rate of patients and transplanted organs. will definitely be helpful in the treatment of patients suffering from end-stage liver disease.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 533
- adults
- elective surgery
- American Society of Anesthesiologists (ASA) physical status classification system I, II, III
- American Society of Anesthesiologists (ASA) physical status classification system IV, V
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description paired remote ischemic preconditioning group remote ischemic preconditioning (RIPC) patients who receive remote ischemic preconditioning
- Primary Outcome Measures
Name Time Method Incidence of postreperfusion syndrome during surgery mean blood pressure decreases by 30% based on the value on preoperative day
- Secondary Outcome Measures
Name Time Method