Prophylactic effect of Tranexamic acid in decreasing hemorrhage in elective cesarean sectio
- Conditions
- Post partum hemorrhage after elective cesarean section.Postpartum hemorrhage
- Registration Number
- IRCT20211109053019N1
- Lead Sponsor
- Karaj University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 200
Singleton pregnancy
Age over 18 years old
Gestational age over 34 weeks
Hemoglobin level before operation over 10 mg/dl
Platelets over 100000
Be an elective cesarean section candidate
Emergency cesarean section
Age less than 18 years old
History of deep vein thrombosis or pulmonary emboli
History of arterial thrombosis( pectoralis angina, myocardial infarction or stroke)
History of convulsion or epilepsy
Any known active cardiovascular or liver or kidney disorder
Autoimmune disease
Sickle cell disease
Severe bleeding disease
Placenta previa
Placenta accreta spectrum
Preeclampsia or eclampsia
Gestational hypertension or chronic hypertension
Hemolysis or low platelet
Intrauterine fetal death
Allergy to tranexamic acid
Multifetal pregnancy
Sever polyhydramnios
History of recurrent abortion
Uterine fibroma
History of rheumatologic disease
Varicose veins
Pre partum hemorrhage
Sever intra abdominal adhesions during surgery
Damage to bladder or intestines or other organs during surgery
Unsuccessful operative vaginal delivery
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement of hemoglobin after cesarean section. Timepoint: 24 hours after surgery. Method of measurement: Using laboratory vein blood samples.
- Secondary Outcome Measures
Name Time Method Post partum hemorrhage. Timepoint: 24 hours after delivery. Method of measurement: Comparison of hemoglobin before and after surgery and using the formula to estimate the amount of bleeding.