Assessment of effect of Tranexamic acid on hemorrhage reduction in hysterectomy
Phase 3
- Conditions
- Condition 1: Hysterectomy. Condition 2: Blood transfusion. Condition 3: Tranexamic acid.Acquired absence of both cervix and uterusZ90.710
- Registration Number
- IRCT20210703051769N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
Candidate of vaginal or abdominal hystrectomy
Between 35-70 years old
American society of anesthesiologist (ASA) grade for physical status 1 or 2
Exclusion Criteria
Anemia
Hepatic dysfunction
Renal dysfunction
Serious cardiac disease
Serious respiratory disease
Acquired or congenital coagulopathy
Previous history of deep venus thrombosis or thromboembolic disease
ASA more than 2
Sensitive to tranexamicacid
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood loss. Timepoint: During and after sugery. Method of measurement: During the surgery by weighting swabs,spinges,operative drapes and measuring the volume in suction buttles after surgery by measuring the drain collectors in post anesthesia care unit.;Blood transfusion. Timepoint: During and 12 hours after surgery. Method of measurement: Pack cell.
- Secondary Outcome Measures
Name Time Method Hemoglobin. Timepoint: During and 12 hours after surgery. Method of measurement: Blood test.;Hematocrit. Timepoint: Before and 12 hours after surgery. Method of measurement: Blood test.;Operation time. Timepoint: Operation time. Method of measurement: Timer.