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Evaluation of the intravenous tranexamic acid effect on blood loss and surgical field quality during nasal surgery

Not Applicable
Conditions
heamorrhage.
Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care During surgical operation
Registration Number
IRCT2013012911822N3
Lead Sponsor
Vice chancellor for Research and Technology, Hamadan University of Medical Science
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
70
Inclusion Criteria

Nasal surgery; 18 to 65 years old; ASA = II
Exclusion criteria: Patient refuse; Surgery time less than 30 minutes; Renal dysfunction; Impaired color vision; Abnormal coagulation test; History of thrombosis or deep vein thrombosis; Ischemic heart disease and arrhythmia; Central nerve system disorder; Allergy to tranexamic acid; Usage Herbal medications; Pregnancy

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Volume of blood in suction bottle. Timepoint: At end of surgery. Method of measurement: Viewing chamber volume per ml.;Quality of hemorrhage. Timepoint: each 20 min. Method of measurement: Boezzart criteria.;Hematocrit. Timepoint: Preoperative and six hours postoperative. Method of measurement: Automated Cell Counter.;Hemoglobin. Timepoint: Preoperative and six hours postoperative. Method of measurement: Automated Cell Counter.;Satisfactory of surgeon from bleeding. Timepoint: At end of surgery. Method of measurement: ask the surgeon.
Secondary Outcome Measures
NameTimeMethod
Impaired color vision. Timepoint: the day after sugery. Method of measurement: Ask the patient.;Nausea. Timepoint: The day after sugery. Method of measurement: Ask the patient.;Vomiting. Timepoint: The day after sugery. Method of measurement: Ask the patient.;Seizure. Timepoint: The day after sugery. Method of measurement: observation of the patient.
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