Socket Preservation After Surgical Extraction of Impacted Lower Third Molar

Not Applicable

Completed

• Conditions: Socket Preservation
• Interventions: Biological: socket preservation using dentine graft mixed with i-PRF; Biological: socket preservation using bone allograft; Biological: socket preservation using collagen cone

• Registration Number: NCT06716736
• Lead Sponsor: Wael Mohamed

Brief Summary

The aim of this study will be to evaluate socket preservation using autogenous particulate dentin in combination with liquid platelet-rich fibrin versus bone allografts and collagen cone after surgical extraction of the horizontally impacted lower third molar

Detailed Description

The aim of this study will be to evaluate socket preservation using autogenous particulate dentin in combination with liquid platelet-rich fibrin (sticky tooth) versus bone allografts and collagen cone after surgical extraction of the horizontally impacted lower third molar

Study Timeline

• Study Start: 2022-12-01
• Primary Completion: 2023-12-15
• Study Completion: 2024-04-01
• Status Verified: 2024-11
• Study First Submitted: 2024-11-29
• Study First Submitted QC: 2024-11-29
• Last Update Submitted: 2024-11-29
• Study First Posted: 2024-12-04
• Last Update Posted: 2024-12-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

1. Fresh extracted socket of horizontally impacted mandibular third molar
2. Co-operative patients willing to complete the follow-up periods.
3. Patients age from 18-35 years.
4. Good oral hygiene.

Exclusion Criteria

1. Any pathological condition at the site of surgery.

2. Patients with systemic diseases that contra-indicate the surgical procedure such as uncontrolled diabetes mellitus, bleeding disorders, serious osseous disorders and mental disorders.

3. Smokers .

4. Pregnancy.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
socket preservation with dentine graft mixed with liquid platelet rich fibrin (sticky tooth)	socket preservation using dentine graft mixed with i-PRF	socket preservation with dentine graft mixed with liquid platelet rich fibrin (sticky tooth) after surgical extraction of horizontally impacted lower wisdom
socket preservation with bone allograft	socket preservation using bone allograft	socket preservation with bone allograft after surgical extraction of horizontally impacted lower wisdom
socket preservation with collagen cone	socket preservation using collagen cone	socket preservation with collagen cone after surgical extraction of horizontally impacted lower wisdom

Primary Outcome Measures

Name	Time	Method
bone resorption distal to second molar	3 months after extraction	by measuring bone level immediate and 3 months after extraction on CBCT

Secondary Outcome Measures

Name	Time	Method
bone density	3 months after extraction	using CBCT 3 month after extraction
edema	4 days after extraction	by measuring distance between predetermined anatomical landmarks: * Mandibular angle and canthus of the eye.; * Mandibular angle and corner of the mouth.; * Mandibular angle and tragus.; * Mandibular angle and pogonion.
pain after surgical extraction	4 days after extraction	using numerical rating scale

Trial Locations

Locations (1)

Mansoura University; 🇪🇬 Mansoura, Eldakahlia, Egypt