Socket Preservation Using Autogenous Bone Graft Versus MPM

Phase 1

• Conditions: Bone Graft; Complications
• Interventions: Other: MPM(Mineralized plasmatic matrix).; Other: Autogenous Bone Graft

• Registration Number: NCT03008538
• Lead Sponsor: Cairo University

Brief Summary

Studying the comparative effectiveness of socket preservation using autogenous bone graft versus MPM for implant insertion.

Detailed Description

To assess bone quality, stability of implants placed in fresh extraction sockets of mandibular anterior and premorals augmented by MPM (Mineralized Plasmatic Matrix) versus autogenous bone graft (gold standard), at different follow-up periods (0, 3, 6, 9 months).

Basic Information
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Recruitment & Eligibility
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Study & Design

Study Timeline

• Study Start: 2016-09
• Status Verified: 2016-12
• Study First Submitted: 2016-12-26
• Study First Submitted QC: 2016-12-30
• Last Update Submitted: 2016-12-30
• Study First Posted: 2017-01-02
• Last Update Posted: 2017-01-02
• Primary Completion: 2017-09
• Study Completion: 2017-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Medically free patients.
2. Patients with mandibular anterior and premolar hopeless teeth indicated for extraction.
3. Evaluated bone height on X.Ray to be (0-4 mm buccal bone dehiscence).
4. Age between 18 and 40 years.
5. Both sexes.
6. Patients physically able to tolerate surgical and restorative procedures. Good oral hygiene.
7. Highly motivated patients.

Exclusion criteria:

1. Smokers.
2. Pregnant or lactating females.
3. Presence of any pathosis in the pre-implant site.
4. Presence of Para functional habits.
5. History of oral radiotherapy.
6. History of prolonged steroids use
7. Psychological disorders.

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Mineralized Plasmatic Matrix	MPM(Mineralized plasmatic matrix).	MPM(Mineralized plasmatic matrix) insertion in extraction sockets for socket preservation for later implant placement and histomorphometric analysis.
Autogenous Bone Graft (Gold Standards).	Autogenous Bone Graft	Socket preservation using Autogenous bone graft for later implant placement and histomorphometric analysis.

Primary Outcome Measures

Name	Time	Method
Patient Satisfaction regarding function, to be measured using patient questionnaire.	3 Months.

Secondary Outcome Measures

Name	Time	Method
Comparative histomorphometric analysis, to be measured using a digital software called (leica QWin 500) and unit of measurements are to be (Pixels).	3 Months.