Effect of dopamine receptor agonists on treatment-resistant depressio
Not Applicable
- Conditions
- treatment-resistant depression
- Registration Number
- JPRN-UMIN000002334
- Lead Sponsor
- Department of Psychiatry, Hokkaido University Graduate School of Medicine
- Brief Summary
Pramipexole was effective for treatment-resistant depression in our small open study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
1) allergy for dopamine agonists, 2) allergy for antidepressants, 3) severe psychotic symptoms, 4) consciousness disturbance, 5) severe hypotension, 6) severe physical disease (heart, lung, liver, kidney, bone marrow, endocrine), 7)peripheral vascular disease, 8) active ulcer, 9) pregnancy, breast-feeding, 10) subjects, whom investigators consider inappropriate
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hamilton Depression Rating Scale (HDRS), Montgomery-Asberg Depression Rating Scale (MADRS)
- Secondary Outcome Measures
Name Time Method Global Assessment of Functioning (GAF), side effects, FDG-PET, MRI, plasma HVA