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Effects of dietary interventions rich in different types of fiber alone or in combination with aerobic exercise on gut microbiota, cardiometabolic health and cognitive function in young adults with overweight or obesity

Phase 1
Conditions
Obesity, Cardiometabolic Health, Cognitive Function
Registration Number
ChiCTR2400088756
Lead Sponsor
School of Public Health, Sun Yat-sen University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1)Undergraduate students at Sun Yat-sen University, Guangzhou;<br>2)BMI = 24 kg/m^2;<br>3)Weight stability in the three months prior to the study (weight fluctuation < 5 kg);<br>4)Willing to participate and able to strictly adhere to the intervention protocol, cooperate with the staff to complete activity check-in tasks according to the activity schedule, and voluntarily sign an informed consent form.

Exclusion Criteria

1)Participated in other weight loss programs in the past three months;<br>2)Used antibiotics continuously for 7 days or more in the past three months;<br>3)Suffer from secondary obesity caused by medication, illness, or other factors;<br>4)Have a history of brain injury or mental illness;<br>5)Have a serious illness affecting major organs or have mobility impairments.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Weight;Waist;Body Fat;Fasting Blood Glucose;Fasting Insulin;Uric Acid;Nutrients;Blood lipid;Iron metabolism;Hypersensitive C-Reactive Protein;Tumor Necrosis Factor-a;Interleukin-6;Interleukin-8;Brain Derived Neurotrophic Factor;Adiponectin;Monocyte Chemotactic Protein-1;Vascular Cell Adhesion Molecule-1;Scores of Prospective and Retrospective Memory Questionnaire;Behavior Rating Inventory of Executive Function;Anxiety;Depression;
Secondary Outcome Measures
NameTimeMethod
Metabolomics;Gut microbiota;
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