Diet as a therapeutic target in depression: A randomised controlled trial

Not Applicable

Completed

• Conditions: Major Depression; Mental Health - Depression

• Registration Number: ACTRN12612000251820
• Lead Sponsor: Barwon Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-02-29
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 176

Inclusion Criteria

Aged 18 or over; have the capacity to consent to the study and to follow its instructions and procedures; fulfil the DSM-IV-TR diagnostic criteria for Major Depressive Disorder, Single Episode or Recurrent, as well as scoring 18 or over on the MADRS at the time of entry into the study. Antidepressant therapy is not an inclusion criterion; however, those on antidepressant therapy need to have been on the same treatment for at least two weeks prior to randomisation. Habitual diet quality will be assessed at screening using the validated Dietary Screening Tool (DST), and only those below the predetermined cutoff (less than 60= categorized as at risk”) will be eligible for the study

Exclusion Criteria

A concurrent diagnosis of bipolar I or II disorder; two or more failed trials of antidepressant therapy for the current major depressive episode; known or suspected clinically unstable systemic medical disorder; pregnancy or breastfeeding; commencement of new psychotherapy; current participation in an intervention targeting diet or exercise; a primary clinical diagnosis of a personality disorder or a current substance use disorder on structured interview.

Study & Design

• Study Type: Interventional
• Study Design: Not specified