Evaluation of efficacy of nebulized Dexamethasone vs nebulized Ketamine on postoperative sore throat in patients undergoing thyroid surgeries.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- To compare the effectiveness of both nebulized Ketamine and nebulized Dexamethasone on post operative sore throat in patients undergoing thyroid surgeries.
研究概览
简要总结
This study is a comparative, prospective, parallel group double blinded study. this study consists of 3 groups (C,D,K) where K group will receive 5 ml of normal saline as nebulization,D group will receive 8mg of Dexamethasone diluted with 3ml of Normal saline as nebulization and group K will receive 50mg of Ketamine diluted with 4ml of normal saline as nebulization. 90 patients posted for thyroid surgeries under general anaesthesia will be equally divided into 3 groups, 30 each. This study will be conducted in Shri B M Patil medical College, Vijayapura, Karnataka. The primary outcome is to compare the effectiveness of both the nebulized Ketamine & nebulized Dexamethasone on post operative sore throat in patients undergoing thyroid surgeries under general anaesthesia. The secondary outcome is to evaluate the effect of nebulizations on hemodynamic parameters.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients undergoing thyroid surgeries under general anaesthesia with ASA grade 1,2.
排除标准
- •Patient refusal.
- •patients with chronic obstructive pulmonary disease.
- •Allergic history to study drug Anticipated difficult intubation and mallampati grade more than 2 History of preoperative sore throat Surgeries lasting beyond 90mins.
结局指标
主要结局
To compare the effectiveness of both nebulized Ketamine and nebulized Dexamethasone on post operative sore throat in patients undergoing thyroid surgeries.
时间窗: 24 hours
次要结局
- To evaluate the effect of nebulization (Ketamine & Dexamethasone) on hemodynamic parameters.(24 hrs)