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临床试验/CTRI/2025/06/089194
CTRI/2025/06/089194尚未招募1 期

Impact of Upper limb Vs Lower limb Exercise Training on Respiratory Function in subjects with Chronic Obstructive Pulmonary Disease

K.SARASWATHI1 个研究点 分布在 1 个国家目标入组 135 人开始时间: 2025年7月16日最近更新:

试验速览

阶段
1 期
状态
尚未招募
发起方
入组人数
135
试验地点
1
主要终点
PULMONARY FUNCTIONS,DYSPNEA,EXERCISE CAPACITY,BMI

研究概览

简要总结

This experimental study aims to evaluate the effects of upper limb training, lower limb training and conventional physiotherapy exercises on respiratory functions in subjects with stable moderate COPD aged 40-50 years.The study will be conducted at the out patient department of Faculty of physiotherpay,ACS Medical College and Hospital,which involves 135 male subjects divided into three groups of 45 participants each, undergoing 45-minute sessions four times weekly over a period of 12 weeks. The primary aim is to investigate the effects of these interventions on pulmonary functions, with the primary objective being a comparative analysis of the impact of upper limb versus lower limb training on pulmonary functions. Secondary objectives include assessing the individual effects of each intervention llike upper limb training, lower limb training and conventional physiotherapy on these parameters. Outcome measures encompass pulmonary functions, dyspnea, exercise capacity, BMI and muscle strength. The results, which will be revealed after the intervention period, are intended to identify the most effective physiotherapy approach for improving respiratory health and functional capacity in subjects with COPD.

研究设计

研究类型
Interventional
分配方式
Stratified block randomization
盲法
Participant and Outcome Assessor Blinded

入排标准

年龄范围
40.00 Year(s) 至 50.00 Year(s)(—)
性别
Male

入选标准

  • 1.Male persons with an Age group between 40 -50 years 2.Subjects with a clinical diagnosis of moderate COPD, according to the global initiative for chronic obstructive lung disease criteria and with stable condition (that is optimal and stable respiratory medications with no exacerbation or hospital admission within the previous month) 3.Forced Expiratory Volume in first second / Forced vital capacity ratio (FEV1 / FVC) 50-60%.
  • 4.Those who had not attended a pulmonary rehabilitation program in the last year.

排除标准

  • 1.Persons with severe or unstable cardiac disease (eg, left-ventricular failure or atrial fibrillation) 2.Clinically unstable COPD i.e., who presented changes in medication dose or frequency, disease exacerbation or hospital admissions in the preceding 8 weeks.
  • 3.Any other comorbidities (severe cardiovascular, neurological or musculoskeletal conditions)that might influence the execution of exercise.
  • 4.Fracture/any other diseases that prevents upper limb and lower limb exercises.

结局指标

主要结局

PULMONARY FUNCTIONS,DYSPNEA,EXERCISE CAPACITY,BMI

时间窗: PULMONARY FUNCTIONS,DYSPNEA,EXERCISE CAPACITY,BMI

次要结局

  • muscle strength(muscle strength)

研究者

发起方
K.SARASWATHI
申办方类型
Other [self]

研究点 (1)

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