Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery

Not Applicable

Completed

• Conditions: Lumbar Spinal Stenosis; Lumbar Disc Herniation; Lumbar Radiculopathy
• Interventions: Drug: Tylenol

• Registration Number: NCT04042948
• Lead Sponsor: Peking University Third Hospital

Brief Summary

This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the preventive use of non-steroidal anti-inflammatory drugs could decrease the possibility of fever happening when we remove the tube.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-06-24
• Study First Submitted: 2019-07-13
• Study First Submitted QC: 2019-07-31
• Study First Posted: 2019-08-02
• Primary Completion: 2019-11-30
• Study Completion: 2019-12-30
• Status Verified: 2021-06
• Last Update Submitted: 2021-06-17
• Last Update Posted: 2021-06-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 183

Inclusion Criteria

• adult patient
• diagnosis of lumbar spinal stenosis
• perform decompression and fusion surgery and lay a drainage tube
• understand the test and could sign the name

Exclusion Criteria

• beside the inclusion criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Experimental Group	Tylenol	preventive use non-steroidal anti-inflammatory drugs to before the removal of drainage tube

Primary Outcome Measures

Name	Time	Method
the rate of fever after the removal of drainage tube	24 hours	we test the temperature of the patient in 24h after the removal of tube, we define fever if the temperature is higher than 37.8 degree

Secondary Outcome Measures

Name	Time	Method
the temperature	24 hours	we compare the change of the level of temperature of two groups in 24h after the removal of the drainage tube
the level of WBC	24 hours	we compare the change of the level of WBC of two groups in 24h after the removal of the drainage tube
the level of CRP	24 hours	we compare the change of the level of CRP of two groups in 24h after the removal of the drainage tube
the level of ESR	24 hours	we compare the change of the level of ESR of two groups in 24h after the removal of the drainage tube

Trial Locations

Locations (1)

Peking University Third Hospital; 🇨🇳 Beijing, Haidian, China