Nalbuphine versus Fentanyl as an Intrathecal Adjuvant to Hyperbaric Bupivacaine in Lower Limb Orthopaedic Surgeries

Veer Surendra Sai Institute of Medical Sciences and Research1 个研究点分布在 1 个国家目标入组 60 人开始时间: 2025年5月20日最近更新: 2025年4月26日

试验速览

阶段: 不适用
状态: 尚未招募
发起方
入组人数: 60
试验地点: 1
主要终点: Duration of effective postoperative analgesia provided by intrathecal Nalbuphine and Fentanyl when used as adjuvants to hyperbaric Bupivacaine in patients undergoing lower limb orthopedic surgeries.

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This trial nalbuphine versus fentanyl as an intrathecal adjuvant to hyperbaric bupivacaine in lower limb orthopaedic surgeries will be undertaken to compare the duration of anaesthesia and postoperative analgesia of both the drugs in terms of onset of sensory and motor block and duration of blocks and also compare the hemodynamic stability and incidence of adverse effects of both drugs.

研究设计

研究类型: Interventional
分配方式: Computer generated randomization
盲法: Participant and Investigator Blinded

入排标准

年龄范围: 18.00 Year(s) 至 60.00 Year(s)（—）
性别: All

入选标准

•Patients aged between 18–60 years Belonging to ASA Physical Status I or II Of either sex Undergoing elective lower limb orthopedic surgery under spinal anesthesia.

排除标准

•Patients who did not give informed consent Known hypersensitivity to any of the study drugs Pregnancy Coagulation disorders, spinal deformities, local infection at the puncture site, or contraindications to spinal anesthesia.

结局指标

主要结局

Duration of effective postoperative analgesia provided by intrathecal Nalbuphine and Fentanyl when used as adjuvants to hyperbaric Bupivacaine in patients undergoing lower limb orthopedic surgeries.

时间窗: 24 hours

次要结局

1. To compare the onset time of sensory & motor blockade between the Nalbuphine & Fentanyl groups.(2. To assess the duration of sensory & motor blockade produced by each adjuvant.)

研究者

发起方

Veer Surendra Sai Institute of Medical Sciences and Research

申办方类型

Research institution and hospital

研究点 (1)

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