patients undergoing lower limb orthopaedic surgeries will be participants divided into two groups and they will be given spinal anaesthesia with bupivacaine and nalbuphine in one group and bupivacaine and fentanyl in another group

Not yet recruiting

Conditions: Fracture of shaft of femur,

Registration Number: CTRI/2025/04/085739

Lead Sponsor: Veer Surendra Sai Institute of Medical Sciences and Research

Brief Summary: This trial nalbuphine versus fentanyl as an intrathecal adjuvant to hyperbaric bupivacaine in lower limb orthopaedic surgeries will be undertaken to compare the duration of anaesthesia and postoperative analgesia of both the drugs in terms of onset of sensory and motor block and duration of blocks and also compare the hemodynamic stability and incidence of adverse effects of both drugs.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 60

Inclusion Criteria

Patients aged between 18–60 years Belonging to ASA Physical Status I or II Of either sex Undergoing elective lower limb orthopedic surgery under spinal anesthesia.

Exclusion Criteria

Patients who did not give informed consent Known hypersensitivity to any of the study drugs Pregnancy Coagulation disorders, spinal deformities, local infection at the puncture site, or contraindications to spinal anesthesia.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of effective postoperative analgesia provided by intrathecal Nalbuphine and Fentanyl when used as adjuvants to hyperbaric Bupivacaine in patients undergoing lower limb orthopedic surgeries.	24 hours

Secondary Outcome Measures

Name	Time	Method
1. To compare the onset time of sensory & motor blockade between the Nalbuphine & Fentanyl groups.	2. To assess the duration of sensory & motor blockade produced by each adjuvant.

Trial Locations

Locations (1): Veer Surendra Sai institute of Medical Sciences and research
🇮🇳
Sambalpur, ORISSA, India
Veer Surendra Sai institute of Medical Sciences and research
🇮🇳Sambalpur, ORISSA, India
Dr Sanskruti Purohit
Principal investigator
8280264444
doc.sp09@gmail.com