Clinical study on nutritional matabolism and intestinal flora in patients with heart failure
- Conditions
- heart failure
- Registration Number
- JPRN-UMIN000042054
- Lead Sponsor
- Division of Clinical Nutrition , Shiga University of Medical Science Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Not provided
1) Those who do not agree 2) Minors 3) Patients with malignant tumor complications. If a malignant tumor is found after participating in the study, it will be excluded from the analysis. 4) Patients with chronic obstructive pulmonary disease, hyperthyroidism, hypothyroidism, serious infectious diseases, and other diseases that affect nutritional metabolism. 5) Patients with pacemakers 6) Patients being treated with antibiotics 7) Other patients that the doctor in charge deems inappropriate
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Association between heart failure severity and gut flora, short-chain fatty acid levels
- Secondary Outcome Measures
Name Time Method 1) Relationship between the severity of heart failure and endotoxin and procalcitonin concentrations 2) Relationship between muscle mass and body fat mass and intestinal flora and short-chain fatty acid concentration 3) Relationship between inflammatory cytokines and endotoxin, procalcitonin, and gut flora 4) Relationship between nutritional indicators at admission and inflammatory cytokines 5) Relationship between nutritional index at admission and endotoxin concentration 6) Relationship between nutritional index at admission, intestinal flora, and short-chain fatty acid concentration