Immune Response to Hepatitis B Virus Booster Vaccination After 20-23 Years

Not Applicable

Terminated

• Conditions: Hepatitis B Vaccination
• Interventions: Biological: HBV booster vaccination 1dose

• Registration Number: NCT02166671
• Lead Sponsor: Seoul National University Hospital

Brief Summary

This study will evaluate the humoral and cellular immune responses to a hepatitis B vaccine booster in healthy adults which received a full course of neonatal hepatitis B vaccination 20-23 years ago.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-04-25
• Study First Submitted: 2014-06-16
• Study First Submitted QC: 2014-06-16
• Study First Posted: 2014-06-18
• Primary Completion: 2015-12-31
• Study Completion: 2015-12-31
• Status Verified: 2017-05
• Last Update Submitted: 2017-05-12
• Last Update Posted: 2017-05-15

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 9

Inclusion Criteria

• healthy adults 20-25 years old

Read More

Exclusion Criteria

• Hepatitis B surface antigen (+)
• Hepatitis B core antibody (+)
• any history of liver disorders including hepatitis
• HIV Ag or Ab(+)

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
HBV booster vaccination	HBV booster vaccination 1dose	-

Primary Outcome Measures

Name	Time	Method
change of HBsAb titer	28 days after HBV booster vaccination

Secondary Outcome Measures

Name	Time	Method
HBsAg-specific cell mediated immunity	28 days after HBV booster vaccination

Trial Locations

Locations (1)

Seoul National University Hospital; 🇰🇷 Seoul, Korea, Republic of