A comparison of Phenylephrine Administration between Intravenous Bolus and Slow Injection in Treatment of Spinal Anesthesia-induced Hypotension on Bradycardia and Other Side Effects in Patients Undergoing Cesarean Sectio

Not Applicable

Completed

• Conditions: hypotension; Healthy prenancy; phenylephrine; spinal anesthesia; cesarean section; bolus; slow

• Registration Number: TCTR20160426003
• Lead Sponsor: none

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-04-26
• Study Completion: 2019-07-12
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 58

Inclusion Criteria

1.ASA physical status I or II
2.Age ≥ 18 years old
3.Singleton baby
4.Term pregnancy (GA ≥ 37 weeks)

Exclusion Criteria

1. Pregestational or gestational hypertension
2. Cardiovascular disease
3. Cerebrovascular disease
4. Obstetric complications (eg. abruptio placenta , placenta previa)
5. Known abnormal fetus
6. History use of monoamine oxidase inhibitor (MAOI) or other drugs that prlong heart conduction
7. Other medications except spinal bupivacaine and spinalmorphine before baby delivery

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of bradycardia Immediately after phenylephrine administration and before baby delivery Number and percentage

Secondary Outcome Measures

Name	Time	Method
Incidence of the other side effects Immediately after phenylephrine administration and before baby delivery Number and percentage