The effect of phenylephrine on blood pressure and nausea and vomiting in pregnant wome
Phase 3
- Conditions
- Pregnancy.Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
- Registration Number
- IRCT20191007045023N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 120
Inclusion Criteria
Pregnant women 18-45 years
Pregnant women candidates for cesarean section by spinal anesthesia
ASA Class 1 and 2
Elective cesarean section
Exclusion Criteria
history of allergy to phenylephrine
BMI>30 Kg/M2
hypertension (>140/90 mmHg)
contraindication for spinal anesthesia
severe cardiovascular disease
prematurity
emergency cesarean section
inadequate analgesia after spinal anesthesia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Systolic blood pressure. Timepoint: every two minutes. Method of measurement: sphygmomanometer.;Diastolic blood pressure. Timepoint: every two minutes. Method of measurement: sphygmomanometer.;Heart rate. Timepoint: every two minutes. Method of measurement: puls oxymetrie.
- Secondary Outcome Measures
Name Time Method Arterial pressure. Timepoint: Every two minutes. Method of measurement: Sphygmomanometer.;SPO2. Timepoint: Every two minutes. Method of measurement: Pulse oximetry.;Nausea. Timepoint: One time, imminently after delivery. Method of measurement: Observing.;PH. Timepoint: One time, imminently after delivery. Method of measurement: Blood sample.;PCO2. Timepoint: One time, imminently after delivery. Method of measurement: Blood sample.;HCO3. Timepoint: One time, imminently after delivery. Method of measurement: Blood sample.;Apgar 1. Timepoint: One time, imminently after delivery. Method of measurement: Observing.;Apgar 5. Timepoint: One time, imminently after delivery. Method of measurement: Observing.