Effects of Propofol-Induced Anaesthesia on the ST-segment of the ECG
试验速览
- 阶段
- 不适用
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- ST-segment variations after propofol administration.
研究概览
简要总结
The purpose of this study is to assess the effect of propofol induced general anaesthesia on the ST-segment of the electrocardiogram. This will be realised by retrospectively analysing the ECG-recordings from adult patients undergoing any treatment at the Catheterisation Laboratory. The ST-segment and other ECG measurements from induction of anaesthesia up to 20 minutes later, will be assessed and compared to the baseline values of the respective segments acquired before injecting propofol. It is essential in this study to exclude any patients burdened with the diagnosis, suspicion or family history of Brugada syndrome.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Induction of anaesthesia with propofol
- •Monitored anaesthesia in the CathLab of the Universitair Ziekenhuis Brussel
排除标准
- •Brugada Syndrome or family history of Brugada syndrome
- •Paediatric population (age <18)
- •Patients who did not receive propofol during the procedure
- •Patients who presented with fever (central core temperature >38,0°C)
结局指标
主要结局
ST-segment variations after propofol administration.
时间窗: Baseline ECG will be measured before administration of propofol. ECG will be measured in the 20 minutes following administration of propofol
Determine ST-segment variations in mm (either augmentation or suppression) on the ECG in the 20 minute period after administration of propofol in comparison to the baseline ECG
次要结局
- Additional ECG-segment variations after propofol administration(Baseline ECG will be measured before administration of propofol. ECG will be measured in the 20 minutes following administration of propofol)