A Pilot Study of Functional Optical Coherence Tomography for Ocular Imaging

Completed

• Conditions: Glaucoma; Diabetic Retinopathy; Age-Related Macular Degeneration; Branch Retinal Vein Occlusion; Central Retinal Vein Occlusion
• Interventions: Device: Optical Coherence Tomography

• Registration Number: NCT00556114
• Lead Sponsor: University of California, Irvine

Brief Summary

Growing evidence shows that altered blood flow plays a major role in many vision-threatening diseases including glaucoma, diabetic retinopathy, age-related macular degeneration, Central Retinal Vein Occlusion, and Branch Retinal Vein Occlusion. Optical coherence tomography, an established imaging technique use for eye exam in clinical ophthalmology, provides high-resolution cross sectional images of the retina and has increased our ability to understand many eye diseases.

Detailed Description

Optical Coherence Tomography is a non-invasive technique use a broadband light source to illuminate the area of study with light in the near infrared spectrum, then obtains static images of tissue structure from interference signals of the back-reflected light.

Optical Coherence Tomography a non-contact, non-invasive means of documenting both tissue structure and blood flow changes in ocular disease and can provide high resolution cross-sectional images of tissue structure, direct visualization of blood flow in blood vessels of the eye.

Study Timeline

• Study Start: 2007-01
• Study First Submitted: 2007-11-07
• Study First Submitted QC: 2007-11-07
• Study First Posted: 2007-11-09
• Primary Completion: 2013-07
• Study Completion: 2013-07
• Status Verified: 2022-10
• Last Update Submitted: 2022-10-19
• Last Update Posted: 2022-10-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

• Adult 18 years and older with normal eye, or has been diagnosed with eye disease.

Exclusion Criteria

• Less than 18 years of age.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Optical Coherence Tomography	Optical Coherence Tomography	Optical Coherence Tomography

Primary Outcome Measures

Name	Time	Method
Medical exam tool	24 hours	Optical Coherence Tomography imaging technique of the retina and ability to diagnose and manage many eye diseases

Trial Locations

Locations (1)

Beckman Laser Institute, University of California,Irvine; 🇺🇸 Irvine, California, United States