To study the effect of desflurane and propofol for maintenance anaesthesia on arterial CO2 and end tidal CO2 gradient in laparoscopic donor nephrectomy patientsA randomised prospective comparative study

There have been different of  arterial to end-tidal CO2 gradient (PaCO2-ETCO2) during various laparoscopic and non laparoscopic surgeries. Laparoscopic procedures, where pneumoperitoneum is introduced using CO2, respiratory function and lung gas exchange are affected. Previous studies on laparoscopic procedures have shown differing results concerning pulmonary gas exchange. Our aim is to study the effects of propofol on lung gas exchange as compared with those of desflurane in patients undergoing elective laparoscopic donor nephrectomy so we are using  capnometry and an intravascular blood gas analysis to monitor this gradient in 70 laparoscopic donor nephrectomy patients.Patients who met the inclusion criteria during the pre-anaesthetic check up will be randomly assigned into two equal groups of 35 each with the help of a computer generated table of random numbers and we would compare the values obtained from capnogram with those obtained from a standard arterial blood gas analyser at four time points.