A Clinical Trial to Compare the Effect of Dexmedetomidine and Propofol Infusion for Sedation during Awake Brain Surgery
Not Applicable
- Conditions
- Health Condition 1: null- ASA 1and 2 and3
- Registration Number
- CTRI/2017/06/008852
- Lead Sponsor
- AIIMS NEW DELHI
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
all awake consenting patients undergoing awake craniotomy
Exclusion Criteria
are uncooperative, with diminished levels of consciousness, mental retardation, with anticipated difficult intubation, obstructive sleep apnoea, medical conditions preventing to lie down for many hours, severe bradycardia, any type of atrioventricular block on the ECG, heart failure, and allergy to the study drugs will be excluded from the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the respiratory complications (Hypoventilation, Hypoxia, Hypercarbia, Desaturation SpO2 90%, Airway obstruction) between the two groups <br/ ><br>Timepoint: intraoperative period
- Secondary Outcome Measures
Name Time Method haemodynamic disturbances, pain, nausea/vomiting, brain bulge, seizures, duration of postoperative analgesiaTimepoint: Intraoperatively at: <br/ ><br>1.Baseline <br/ ><br>2.10 minutes after starting infusion <br/ ><br>3.During scalp block <br/ ><br>4.During pin fixation <br/ ><br>5.During skin incision <br/ ><br>6.During bone flap elevation <br/ ><br>7. During dural incision <br/ ><br>8. Dt tumor excision <br/ ><br>9. At dural closure <br/ ><br>10.At skin closure <br/ ><br>Postoperatively when patient will complain pain first time with VAS Score more then 4 after surgery